Imidazo[1,2-a]pyridine, 3-iodo- - Names and Identifiers
Imidazo[1,2-a]pyridine, 3-iodo- - Physico-chemical Properties
Molecular Formula | C7H5IN2
|
Molar Mass | 244.03 |
Density | 2.01±0.1 g/cm3(Predicted) |
Melting Point | 165-170°C |
pKa | 4.15±0.50(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.75 |
Imidazo[1,2-a]pyridine, 3-iodo- - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
|
WGK Germany | 3 |
Hazard Class | IRRITANT |
Imidazo[1,2-a]pyridine, 3-iodo- - Introduction
3-iodoimidazo[1,2-a]pyridine is an organic compound with the chemical formula C7H4IN3. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 3-iodoimidazo[1,2-a]pyridine is a white to yellowish crystalline solid.
-Solubility: It is soluble in common organic solvents.
-Melting point: Its melting point range is 126-129°C.
-Stability: 3-iodoimidazo[1,2-a]pyridine is relatively stable under regular storage conditions.
Use:
- 3-iodoimidazo[1,2-a]pyridine is an important organic synthesis intermediate, which is widely used in the fields of medicine, pesticide and dye.
-It can be used to synthesize other organic compounds, such as anticancer drugs, antimalarial drugs, etc.
Method:
- 3-iodoimidazo[1,2-a]pyridine can be prepared by different synthetic routes. A common method is to first react aniline with a dicarbonyl reactive compound (e. G., amide, imide, etc.) to form an imidazole ring and then introduce an iodine atom by an iodination reaction.
Safety Information:
- 3-iodoimidazo[1,2-a]pyridine has limited toxicity information, but based on its structure and experience with iodine-related compounds, it may be irritating and sensitizing.
-Appropriate safety measures, such as wearing chemical protective goggles, gloves and laboratory coats, should be taken during experimental operations.
-When storing and handling, follow appropriate safety regulations and keep away from ignition and oxidizing agents.
Last Update:2024-04-09 02:00:45